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Updated: Jun 25, 2025

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塞马-3E/PlexinD1轴调节树突细胞表型和功能:当前状态和未来影响

Abdulaziz Alamri1

  • 1Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Human immunology
|May 21, 2024
PubMed
概括

塞马-3E/PlexinD1轴显著影响树突细胞 (DCs),对免疫反应至关重要. 了解这种相互作用为免疫学和临床医学提供了新的治疗途径.

关键词:
细胞因子的生产树突性细胞 树突性细胞免疫调节 免疫调节在Sema-3E和PlexinD1中使用.它的治疗潜力很大.

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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