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Updated: Jun 25, 2025

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通过对Nrf2的上调调节来缓解ROS触发的内质网膜应激,延缓糖尿病病

Xiaojiao Zeng1, Yuanyuan Zhang1, Ling Tian1

  • 1NHC Key Laboratory of Hormones and Development, Chu Hsien-I Memorial Hospital and Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China; Tianjin Key Laboratory of Metabolic Diseases, Tianjin Medical University, Tianjin, 300134, China.

Biochemical and biophysical research communications
|May 21, 2024
PubMed
概括

与NFE2相关的因子-2 (Nrf2) 保护糖尿病病 (DN) 的内细胞网膜应激 (ERS). 抑制Nrf2可能提供一种治疗策略,通过减轻反应性氧物种介导的ERS来延缓DN进展.

关键词:
糖尿病脏病 糖尿病脏病细胞内膜网膜应激压力是什么与NFE2相关的因素2有反应性氧物种的反应性氧物种.

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