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Updated: Jun 25, 2025

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
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联结启动单分子整合素的构成激活

Jing Li1, Myung Hyun Jo2, Jiabin Yan3

  • 1Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|May 21, 2024
PubMed
概括

整合素的激活始于在连接器结合时的外向信号,然后是内向信号. 通过actin细胞骨架的拉力传递对于完全的整合激活至关重要.

关键词:
其他货物内部外信号整合素激活途径整体结构的变化整体结构动力学连接物在外输入信号一个分子其他

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