身体成分变化与糖尿病发展的关联:全国范围的人口研究
Hyung Jun Kim1, Hyung-Woo Lee2, Min-Kyoung Kang2
1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Diabetes & metabolism journal
|May 21, 2024
概括
肌肉质量减少和身体脂肪增加与新发糖尿病 (DM) 有关. 保持健康的身体组成可能有助于预防糖尿病的发展.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 研究了身体组成变化与新发糖尿病 (DM) 之间的联系.
- 专注于使用纵向数据的一般韩国人口.
- 检查了与身体质量指数 (BMI) 分类相对的关联.
研究的目的:
- 为了确定身体组成指标和新发性DM的发病率之间的关系.
- 评估这些关联是否在BMI类别之间存在差异.
- 通过身体成分管理,提供对糖尿病预防策略的见解.
主要方法:
- 利用来自韩国国家医疗保险服务-健康查 (2010-2013) 的大型数据集.
- 包括超过160万参与者没有先前存在的DM.
- 计算预测的尾骨肌肉质量指数 (pASMMI),身体脂肪质量指数 (pBFMI) 和瘦肉体质量指数 (pLBMI) 使用人类学方程.
主要成果:
- 降低pASMMI和pLBMI与男性和女性新发性DM风险更高有关.
- 增加的pBFMI与增加的DM风险有显著的相关性.
- 这些关联在超重和肥胖个体中特别明显,不论性别.
结论:
- 肌肉质量下降 (pASMMI,pLBMI) 和体脂肪增加 (pBFMI) 是新发性DM的危险因素.
- 过多的脂肪积累和肌肉质量的损失有助于糖尿病的发展.
- 优化身体成分有可能预防新发糖尿病.
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