相关实验视频

Updated: Jun 25, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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一个多特征的GWAS识别了影响albuminuria的新基因

Hsiao-Mei Tsao1,2, Tai-Shuan Lai1,2, Yi-Cheng Chang3,4,5

  • 1Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
|May 21, 2024
PubMed
概括

这项研究使用多特征GWAS来识别与白病相关的基因,揭示了新的遗传基因位点,并突出了初级乳毛在功能和白病发育中的作用.

关键词:
在GWAS中,GWAS就是GWAS.专辑蛋白内细胞形成的过程专辑蛋白尿症是什么意思对GWAS的多特征分析主要的乳毛是主要的乳毛.

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Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization08:27

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Published on: July 27, 2021

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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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Pleiotropy01:33

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