使用丰富的乳酸菌 (Lactobacillus brevis LSe) 治愈床痛:一个随机,双盲,受控的临床试验
Farshid Ataollahi1, Bagher Amirheidari2,3,4, Mehdi Ahmadinejad5
1Extremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Biological trace element research
|May 21, 2024
概括
富含的益生菌通过减少愈合时间,显著加速了ICU患者的床愈合. 这项研究表明,富含Se的益生菌可以作为压力的潜在辅助治疗方法.
科学领域:
- 微生物学 微生物学
- 临床医学 临床医学
- 营养科学 营养科学
背景情况:
- 床 (压力) 是一个重要的医疗保健挑战.
- 益生菌,特别是那些富含 (Se) 的益生菌,在伤口愈合和减少炎症方面表现有前途.
- 研究了一种来自传统乳制品的特定丰富益生菌的治疗潜力,用于治疗床.
研究的目的:
- 评估一种富含Se的益生菌在加速I和II阶段病床伤愈合的疗效.
- 为了比较接受Se丰富益生菌与对照组的患者的伤口愈合标准.
- 评估Se丰富益生菌对床患者炎症标志物的影响.
主要方法:
- 进行了一项随机,双盲,受控的临床试验.
- 20名患有I和II阶段病床的ICU患者每天服用Se丰富益生菌,持续14天.
- 在治疗和对照组之间比较了伤口愈合标准,床大小,床等级和实验室炎症参数.
主要成果:
- 富含Se的益生菌组显示,病床愈期的统计显著减少 (平均2.4天,P=0.039).
- 在治疗组中观察到床大小和等级的改善,尽管在统计学上并不显著.
- 与炎症相关的关键实验室参数在接受Se补充益生菌的患者中显示出改善.
结论:
- 富含的益生菌显著减少了病的愈合时间.
- 这项研究表明,富含Se的益生菌可以被认为是治疗压力的有效辅助剂.
- 需要对更大的患者队伍和延长后续进行进一步的研究,以充分阐明益处.
相关概念视频
01:27Microbes in the Production of Fermented Foods
Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
01:22Probiotics
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
01:25Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...