在临时性和外临时性中,不对称的最后一次克隆性冲动的侧面化值和临床放射学特征
Furkan Saridas1, Gizem Mesut2, Yasemin Dinc2
1Department of Neurology, Bursa Uludağ University Medicine Faculty, Bursa, Türkiye. furkansaridas@uludag.edu.tr.
Scientific reports
|May 21, 2024
概括
在焦点到双边强力-克隆性发作 (FBTCS) 中,不对称的最后克隆性 (aLCJ) 有助于确定发作.
科学领域:
- 神经学 神经学
- 发病学 (Epileptology) 是一个专业的学科.
- 临床神经生理学 临床神经生理学
背景情况:
- 发作半球学和电脑电图 (EEG) 对于分类发作类型和确定半球横向化或局部化至关重要.
- 焦点到双边强力克隆性 (FBTCS) 经常为侧面化提供信息性的临床症状,特别是在发作或终止时.
研究的目的:
- 调查非对称的最后一个克隆性冲动 (aLCJ) 与病理,局部化,横向化和半理学发现之间的关系.
- 根据ictalEEG激活来确定半球横向化aLCJ的积极预测值.
主要方法:
- 一项涉及44名LCJ患者和同样数量的没有LCJ的患者的研究,在VEM单位进行了随访.
- 分析与aLCJ相关的半理学发现,神经成像,神经心理测试和阴茎脑电图激活.
主要成果:
- 在患有ipsilateral自动和逆侧姿势或味觉/嗅觉幻觉的患者中,aLCJ不太常见或不存在.
- aLCJ在表现出单边增强活性的患者中更为频繁.
- aLCJ对于ictalEEG激活横向化的积极预测值为86.36%.
结论:
- 不对称的最后一个克隆节拍是FBTCS横向化的一个有价值的临床标志.
- 一个LCJ的存在强烈且可靠地将发作的发作横向到两侧半球.
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