在乳腺甲状腺癌的横向淋巴结转移中,jugulo-omohyoid淋巴结的预测值
Huizhu Cai1, Lingdun Zhuge1, Zehao Huang1
1Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
BMC endocrine disorders
|May 21, 2024
概括
朱古洛-奥莫腺淋巴结 (JOHLN) 转移是乳头甲状腺癌 (PTC) 中侧面淋巴结转移 (LLNM) 的敏感预测因素. 一个开发出来的诺姆图有助于评估个体的LNM风险,并指导手术决策.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 头部和部手术 头部和部手术
背景情况:
- 朱古洛-状腺淋巴结 (JOHLN) 转移与乳头甲状腺癌 (PTC) 的侧面淋巴结转移 (LLNM) 有关.
- 了解JOHLN转移有助于确定PTC患者手术的程度.
研究的目的:
- 研究PTC中JOHLN转移的临床特征.
- 评估JOHLN转移对LLNM的预测价值.
- 根据JOHLN状态指导手术程度.
主要方法:
- 对550名经过甲状腺切除和横向淋巴结解剖的PTC患者进行了回顾性分析.
- 统计分析以确定JOHLN转移和LLNM的风险因素.
- 开发和验证一个预测名ogram.
主要成果:
- 与JOHLN转移相关的因素包括甲状腺炎,瘤位置,大小,甲状腺外延伸,结节外延伸,中枢淋巴结转移 (CLNM) 和LLNM.
- 独立的LLNM风险因素是男性性别,上叶瘤,多焦点,额外节点延伸,CLNM和JOHLN转移.
- 纳入这些因素的诺米图表显示出良好的预测性能 (AUC=0.855),神经入侵和JOHLN转移是关键预测因素.
结论:
- 约翰转移是进一步横向淋巴结转移 (LLM) 的临床敏感预测因素.
- 开发了一种高性能的诺姆图,用于对淋巴结转移 (LNM) 的个性化风险评估.
- 诺米图可以协助PTC患者的治疗决策和手术规划.
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