在中国中老年和老年人中,长期访问的血压变化和抑郁症之间的关联
Jinni Liao1,2, Weida Qiu3, Dan Huang1,2
1Department of General Section II, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Postgraduate medicine
|May 22, 2024
概括
长期血压变化 (BPV) 与中国成年人抑郁症状的增加有关. 较高的血压值,通过变化系数和标准偏差来衡量,与更高的抑郁风险相关,特别是在男性中.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 在中国成年人中,长期血压变化 (BPV) 和随后的抑郁症之间的纵向关联尚未得到充分证实.
- 了解这种联系对于老龄化人口的公共卫生战略至关重要.
研究的目的:
- 研究长期血压变化 (BPV) 与45岁以上中国成年人抑郁症状发生率之间的关联.
- 为了确定BPV的特定模式,可以预测未来的抑郁症.
主要方法:
- 利用了来自中国健康与退休纵向研究 (CHARLS) 队列的数据.
- 测量了长期的BPV使用内部个体变化系数 (CV) 和标准偏差 (SD) 在三个访问 (2011-2015年) 的静缩和放缩血压.
- 使用10项流行病学研究中心抑郁症尺度 (CES-D-10) 评估抑郁症状,将中度至重度抑郁症定义为CES-D-10 ≥15.
主要成果:
- 总共分析了5249名参与者 (平均年龄为61.4岁).
- 较高的BPV四分位数 (CV和SD) 独立地与较高的CES-D-10总分数相关.
- 与最低四分位数相比,SBP CV和DBP CV最高四分位数的参与者患中度至重度抑郁症的几率明显更高 (分别为1.23倍和1.20倍).
- 亚组分析表明,高血压值的男性患重度抑郁症状的风险更高.
结论:
- 长期访问访问的BPV与中年和老年中国人的抑郁症状有关.
- 这些发现强调了监测BPV对于预防抑郁症的重要性.
- 在中国,建议加强血压监测和针对性干预.
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