孕产妇的出生体重是早产的一个指标:日本环境和儿童研究
Rie Kudo1, Noriyuki Iwama1,2, Hirotaka Hamada1
1Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan.
概括
在日本,母亲的出生体重 (MBW) 与早产 (PTD) 相反相关. 较低的MBW增加了早产和晚产早产的风险,突出了它对妊娠结果的重要性.
科学领域:
- 产科和妇科 产科和妇科
- 围产期流行病学 围产期流行病学
- 生殖健康 生殖健康
背景情况:
- 孕产妇的出生体重 (MBW) 是妊娠结果的潜在决定因素.
- 在亚洲人群中,MBW和早产 (PTD) 之间的关联存在有限的数据.
研究的目的:
- 在一个大型的日本队列中,调查母亲出生体重 (MBW) 和早产 (PTD) 之间的关联.
- 检查 MBW 与早产和晚产的关系.
主要方法:
- 一项前性分娩队列研究包括78,972名日本孕妇.
- 用物流回归和多项物流回归模型来分析数据.
- 关联被调整以考虑潜在的混因素.
主要成果:
- 孕产妇的出生体重与PTD,早期PTD和晚期PTD (p-for-trend < 0.0001) 相反相关.
- 在MBW中减少500g与PTD (aOR=1.167),早期PTD (aOR=1.174) 和晚期PTD (aOR=1.151) 的几率增加有关.
- 早期和晚期PTD的效果大小相似.
结论:
- 这项全国性的日本研究表明,母亲的出生体重与早产之间存在显著的反向关联.
- 较低的产妇出生体重是早期和晚期早产的风险因素.
- 这些发现强调了在评估早产风险时考虑母亲出生体重的重要性.
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