工作负载和运动诱导的心脏托波激素升高之间的关系受非阻塞性冠状动脉样硬化影响
Magnus Bjorkavoll-Bergseth1,2, Christine Erevik1, Øyunn Kleiven1
1Department of Cardiology, Stavanger University Hospital, Stavanger, Norway.
Scandinavian journal of medicine & science in sports
|May 22, 2024
概括
运动诱导的心脏Troponin I (cTnI) 升高与非阻塞性冠状动脉疾病 (CAD) 的运动员的工作负担有关. 这表明,即使没有显著的动脉阻塞,CAD也会影响cTnI反应.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 运动生理学 运动生理学
背景情况:
- 运动可以导致热素升高,但其与非阻塞性冠状动脉疾病 (CAD) 的关系尚不清楚.
- 评估运动员的激素水平对于区分运动引起的变化和潜在的心脏事件至关重要.
- 非阻塞性CAD可能会影响心肌对高强度运动的反应.
研究的目的:
- 研究非阻塞性CAD对中年休运动员运动诱导的心脏Troponin I (cTnI) 升高的影响.
- 为了确定非阻塞性CAD的存在是否会改变运动工作量和cTnI反应之间的相关性.
- 探索运动强度,持续时间和cTnI水平在有和没有动脉样硬化症的运动员之间的关系.
主要方法:
- 观察性研究涉及40名训练有素的休运动员 (50±9岁).
- 高灵敏心脏Troponin I (cTnI) 测定用于测量24小时前,3小时和24小时后两个高强度运动的水平:心肺运动测试 (CPET) 和91公里山地自行车比赛.
- 冠状动脉计算机断层扫描血管图 (CCTA) 用于识别非阻塞性CAD (<50%阻塞).
主要成果:
- 运动后cTnI水平在山地自行车比赛后明显高于CPET在3小时和24小时.
- 在非阻塞性CAD的运动员 (n=15) 和没有阻塞性CAD的运动员 (n=25) 之间,绝对cTnI值没有差异.
- 在非阻塞性CAD组与正常组相比,在运动后3小时和24小时,在cTnI反应和运动工作量之间观察到明显更强的正相关性.
结论:
- 运动诱导的cTnI升高与中年运动员中非阻塞性CAD的运动工作负荷有很强的相关性.
- 非阻塞性CAD的存在似乎影响了运动工作量和cTnI反应之间的关系,即使没有显著的冠状动脉阻塞.
- 这些发现凸显了在解释运动诱导的运动员肌激素升高时考虑潜在的CAD的重要性.
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