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使用单分子导电量测量方法识别SARS-CoV-2变种

Zahra Aminiranjbar1, Caglanaz Akin Gultakti2,3, Mashari Nasser Alangari1,4

  • 1Department of Electrical and Computer Engineering, University of California Davis, Davis, California 95616, United States.

ACS sensors
|May 22, 2024
PubMed
概括

单分子RNA导电实验可以快速识别特定的SARS-CoV-2变体. 这种方法使用机器学习来检测遗传变化,有助于跟踪新的菌株,如Alpha,Beta,Delta和Omicron.

关键词:
检测SARS-CoV-2变种的检测方法机器学习XGBoost机器学习生物传感器生物传感器分子电子学分子电子学单分子断裂连接点的断裂连接点.

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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