在长期COVID患者中探索心力衰竭的联系:叙述性审查
Emmanuel Olumuyide1, Chibuike C Agwuegbo2, Eman N Ahmed3
1Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, USA.
Cureus
|May 22, 2024
概括
长期COVID患者由于系统性炎症和内皮功能障碍,患心力衰竭 (HF) 的风险增加. 早期的多学科护理对于管理这种复杂的心血管并发症至关重要.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 长期COVID是SARS-CoV-2感染后的一种疾病,它带来了各种长期健康问题.
- 心力衰竭 (HF) 是一种已知的,但复杂的,与长期COVID相关的心血管并发症.
- 将长期COVID与HF和诊断挑战联系在一起的精确机制需要进一步阐明.
研究的目的:
- 审查长期COVID和患心力衰竭 (HF) 的风险之间的关系.
- 探索长期COVID相关高血压的病理生理机制.
- 讨论长期COVID患者中HF的诊断挑战和管理策略.
主要方法:
- 关于长期COVID和心血管并发症的现有文献的叙事综述.
- 分析拟议的病理生理路径,包括炎症和内皮功能障碍.
- 检查诊断困难和生物标志物的作用.
主要成果:
- 长期的COVID显著增加患心力衰竭 (HF) 的风险.
- 病理生理学涉及系统性炎症,内皮功能障碍,补体和组织因子通路激活,以及血栓形成.
- 由于不可靠的生物标志物对先前存在的和COVID-19诱导的HF产生了诊断挑战.
结论:
- 长期的COVID通过炎症和血栓性机制构成心力衰竭 (HF) 的重大风险.
- 多学科护理对于管理长期COVID相关的HF至关重要.
- 需要进一步的研究来完善COVID-19后的长期心血管健康的诊断工具和治疗策略.
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