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在韩国中风患者中,与辅酶Q10相关的遗传多态性和他类药物相关的肌肉毒性之间的关联

Yoon-A Park1, Yoonkyung Chang2, Da Hoon Lee1

  • 1College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.

Frontiers in pharmacology
|May 22, 2024
PubMed
概括

某些辅酶Q10 (CoQ10) 基因变异显著增加了与他类药物相关的神经毒性 (SRM) 的风险. 识别这些遗传因素可以帮助个性化他类药物治疗,以减少不良影响.

关键词:
辅酶Q10是Q10的代酶之一.肌肉毒性 肌肉毒性 肌肉毒性药物基因组学 药物基因组学多态的多态化.斯塔丁斯塔丁斯是一个国家.

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