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光电脉冲扫描和心内压力:来自试点研究的早期见解

Niels T B Scholte¹, Annemiek E van Ravensberg¹, Roos Edgar²

¹Department of Cardiology, Cardiovascular Institute, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands.

European heart journal. Digital health

|May 22, 2024

概括

来自手腕可穿戴设备的非侵入性光聚体图 (PPG) 可以通过肺毛细血管压 (PCWP) 来分类心力衰竭患者. 这项试点研究显示了可访问,早期HF监测的潜力,减少住院治疗.

科学领域:

生物医学工程生物医学工程
心脏病学心脏病学
可穿戴技术可穿戴技术

背景情况:

对心力衰竭 (HF) 的侵入性血液动力学监测对于早期检测和住院预防至关重要,但成本昂贵且难以获得.
需要一种可靠的,非侵入性的替代方法来监测肺毛细血管压 (PCWP) 在HF患者.

研究的目的:

为了研究手腕衍生型光电显微镜 (PPG) 信号与侵入性测量PCWP之间的关系.
评估使用可穿戴PPG在HF患者中进行非侵入性PCWP评估的可行性.

主要方法:

一项试点研究包括14名患有大动脉狭窄症的患者,这些患者正在接受跨导管大动脉置换.
提取了六个PPG信号特征 (心率,HRV,SA,扩张幅度,CT,LASI).
使用回归和分类模型来估计和分类PCWP (<12 mmHg与≥12 mmHg).

主要成果:

回归模型显示PPG特征与连续PCWP之间的相关性很低.
分类模型表现出更高的性能:SA和LASI模型的AUC为0.86,CT模型的AUC为0.72.
这些发现表明PPG在非侵入性地对PCWP进行分类的能力.

结论:

手腕佩戴的PPG设备可以非侵入性地将患者分类为临床相关的PCWP类别.
建议在更大的高频队列进行进一步的研究,以探索PPG在高频管理方面的全部潜力.

关键词:

心脏衰竭是因为心脏衰竭.心内压力心内压力摄影电解质量学摄影电解质量学远程医疗远程医疗可穿戴设备可以穿戴.

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