解码230万个ECG:可解释的深度学习,以推进心血管诊断和死亡风险分层
Lei Lu1,2, Tingting Zhu1, Antonio H Ribeiro3
1Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, OX3 7DQ, UK.
European heart journal. Digital health
|May 22, 2024
概括
人工智能 (AI) 模型可以解释心电图 (ECG) 以获得准确的心脏诊断和死亡风险分层. 这种深度学习方法推进了心血管疾病的评估,并从心电图数据中发现了新的临床见解.
科学领域:
- 心脏病学 心脏病学
- 医疗人工智能 医疗人工智能
- 计算生物学 计算生物学
背景情况:
- 电心电图 (ECG) 对于评估心血管疾病至关重要.
- 人工智能 (AI) 在解释新临床见解的ECG中的应用仍然未被充分探索.
- 人工智能有可能提高使用心电图数据的诊断准确性和风险分层.
研究的目的:
- 开发和验证一个深度学习模型,用于细粒度的心电图解释.
- 推进心血管诊断,死亡风险分层,并从ECG中识别新的临床信息.
- 探索AI在使用ECG进行性别识别和高血压查方面的能力.
主要方法:
- 使用了来自1,558,772名患者的2,322,513个心电图的大数据集.
- 开发了一个深度学习模型,用于可解释的诊断,性别识别和高血压查.
- 模型的性能使用接收器运行特征曲线下的面积 (AUC) 和危险比率 (HR) 来评估.
主要成果:
- 人工智能模型在诊断任务中获得了高AUC得分 (高达0.998).
- 电脑心电图预测结果发现,鼻高心率和心房动的高死亡风险.
- 在高血压患者的高血压查和死亡风险分层方面,V1心电图的领先结果是至关重要的.
结论:
- 人工智能模型表明,仅使用心电图,心脏病诊断和死亡风险分层的准确性达到心脏病学家水平.
- 该模型有可能促进性别和高血压检测的临床知识发现.
- 这种人工智能方法将心血管诊断和风险评估推进到传统方法之外.
相关概念视频
01:29Electrocardiogram
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An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
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01:28Electrocardiogram Fundamentals
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Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
566
01:24ECG Interpretation of Rhythms
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An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
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01:17Imaging Studies for Cardiovascular System I:Echocardiography
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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
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01:30Pulse rhythm
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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
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