增加的身体质量指数 (BMI) 和在第三级推中心的儿童中发生的无皮炎之间的关联:一个病例对照研究
Adelina-Maria Sendrea1,2,3, Sinziana Cristea4, Carmen Maria Salavastru1,3
1Pediatric Dermatology, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Cureus
|May 22, 2024
概括
患有亚形性皮肤炎 (AD) 的儿童的体重指数 (BMI) 显着更高,更有可能超重或肥胖. 阿兹海默氏症患者的BMI增加与疾病严重程度的增加相关,突出了患有该疾病的儿童需要进行肥胖查的必要性.
科学领域:
- 儿科皮肤病学 儿科皮肤病学
- 公共卫生 公共卫生
- 慢性疾病流行病学 慢性疾病流行病学
背景情况:
- 亚托邦性皮肤炎 (AD) 和肥胖是普遍存在的慢性疾病,与炎症有关.
- 阿尔茨海默病越来越多地被认为是一种系统性疾病,伴有并发症.
- 这项研究调查了儿童超重/肥胖和AD之间的关联.
研究的目的:
- 为了检查身体质量指数 (BMI) 和儿童中亚型皮肤炎 (AD) 的存在之间的关系.
- 评估BMI与亚托皮性皮肤炎的严重程度之间的相关性.
- 为了确定与对照组相比,阿兹海默症儿童中超重和肥胖的流行率.
主要方法:
- 一项病例控制研究,涉及130名患有AD的儿童和130名匹配的对照.
- 评估身体质量指数 (BMI) 使用体重和身高百分比.
- 通过评分无皮炎指数 (SCORAD) 评估阿尔茨海默病的严重程度,通过皮肤病学生活质量指数 (DLQI) 评估生活质量.
主要成果:
- 与对照组相比,患有阿尔茨海默病的儿童的BMI显著更高 (p=0.027).
- 在AD组中,超重/肥胖状态的频率是AD组的三倍 (OR 3.61).
- 增加的BMI与AD严重程度相关 (SCORAD),在中度至严重的AD中,超重/肥胖的风险增加了20倍 (OR 20.4).
结论:
- 这项研究发现罗马尼亚儿童的BMI增加,AD发展和AD严重程度之间存在显著的相关性.
- 医生应该考虑在患有AD的儿童中进行肥胖查,以全面管理.
- 需要进行更大规模的多中心研究来证实这些发现并建立精确的相关性.
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