在患有缺血性心肌病的患者进行两种联合运动训练方案后,左心房功能发生变化:试点研究
Giuseppe Caminiti1,2, Maurizio Volterrani1,2, Ferdinando Iellamo3
1Department of Human Science and Promotion of Quality of Life, San Raffaele Open University, Rome, Italy.
Frontiers in cardiovascular medicine
|May 22, 2024
概括
联合炼训练在患有缺血性心肌病 (ICM) 的患者中改善了左心房功能. 较高频率的训练 (每周三次) 与较低频率或家庭运动相比,对心房功能和血压有更大的益处.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 心脏康复心脏康复
背景情况:
- 左心房功能障碍是缺血性心肌病 (ICM) 的预后指标.
- 运动训练是改善ICM患者心房功能的潜在治疗目标.
- 关于运动对ICM中心房功能的影响的研究有限.
研究的目的:
- 评估12周联合训练 (CT) 计划对ICM患者左心房功能的影响.
- 为了研究运动频率和心房功能改善之间的剂量反应关系.
主要方法:
- 45名稳定的ICM患者被随机分为三个组:低频CT (CTLF,每周两次),高频CT (CTHF,每周三次) 和家庭控制组.
- 所有参与者在基线和12周接受了症状限制性运动测试和心声回声扫描.
- 综合训练包括有氧持续运动和抵抗运动.
主要成果:
- 与对照组相比,CTLF和CTHF组都显示运动测试持续时间增加.
- 只有在CTHF组中,心房纵向应变的峰值显著改善.
- 与CTLF和对照相比,CTHF组的峰值心房收缩应变显著改善.
- 左心室全球纵向应变在CT组和对照组中均有所改善.
- 在两个CT组中,静脉压下降.
结论:
- 联合运动训练有效地改善ICM患者的心房功能.
- 运动训练表明对心房功能的改善有剂量依赖的影响.
- 高频CT可能更有利于增强心房功能和降低ICM中的血压.
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