用标准和先进的心声回声技术评估系统性红斑狼患者的左心室缩功能:系统性综述和元分析
Maka Gegenava1, Zviad Kirtava2, William Kf Kong3
1Department of Internal Medicine №2, Tbilisi State Medical University, Tbilisi, Georgia.
Archives of rheumatology
|May 22, 2024
概括
系统性红斑狼 (SLE) 患者心力衰竭 (HF) 和左心室 (LV) 缩功能受损的风险显著更高. 高级心声回声学,特别是LV全球纵向菌株 (LVGLS),可能有助于在SLE中早期检测心脏功能障碍.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 系统性红斑狼 (SLE) 与心血管并发症有关.
- 左心室 (LV) 缩功能是心脏健康的关键指标.
研究的目的:
- 系统地审查和元分析关于SLE患者LV缩功能的病例控制研究.
- 用标准和先进的心声回声学方法来评估心脏功能.
主要方法:
- 对病例控制研究的系统审查和元分析.
- 按照柯克伦协作和MOOSE指导方针进行文献搜索.
- 包括评估心力衰竭,LV喷射率 (LVEF) 和LV全球纵向菌株 (LVGLS) 的研究.
主要成果:
- 在SLE患者中,高心力衰竭 (HF) 率为2.39%,风险比对照患者高3.4倍.
- 与对照组相比,SLE患者表现出较低的LVEF和更受损的LVGLS.
- 无论心声回声图 (2D或3D) 的维度如何,LVGLS都受到显著影响.
结论:
- 患有SLE的患者面临着大幅增加的高风险.
- 通过LVEF和LVGLS评估的LVV缩功能在SLE中明显受损.
- 作为SLE中LV功能障碍的早期诊断工具,LVGLS显示出希望.
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