风湿性关节炎患者的胸腔厚度和间歇性肺病之间的关联:一个横截面研究
Serdar Kaymaz1, Nilüfer Savurmuş2, Uğur Karasu1
1Department of Internal Medicine, Division of Rheumatology, Pamukkale University Faculty of Medicine, Denizli, Türkiye.
Archives of rheumatology
|May 22, 2024
概括
与没有肺部疾病的患者相比,风湿性关节炎患者在鼻腔区域显示出较薄的胸膜厚度 (CT). 然而,CT与间歇性肺病的严重程度没有相关性.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
背景情况:
- 类风湿性关节炎 (RA) 是一种全身性自身免疫性疾病.
- 与RA相关的间歇性肺病 (RA-ILD) 是影响发病率和死亡率的重大并发症.
- 冠状腺厚度 (CT) 的改变可能表明在炎症性疾病中发生了全身血管变化.
研究的目的:
- 在患有类风湿性关节炎 (RA) 的患者中评估胸腔厚度 (CT).
- 为了比较RA患者与没有间歇性肺病 (RA-ILD) 之间的CT.
- 为了确定CT和RA-ILD严重程度之间的关系.
主要方法:
- 一项横截面研究包括59名RA患者 (20名RA-ILD,39名没有) 和36名健康对照.
- 用五点增强深度成像光学连贯性断层扫描测量胸膜厚度 (CT).
- 使用高分辨率计算机断层扫描 (HRCT) 和肺功能测试来评估RA-ILD的严重程度.
主要成果:
- 与没有ILD的RA患者和健康对照者相比,RA-ILD患者在鼻点的CT显著较薄.
- 鼻部CT测量在RA-ILD组中最低,其次是RA-noILD和健康组.
- 在CT测量和肺功能测试或HRCT发现之间没有发现显著的相关性.
结论:
- 患有RA-ILD的患者在鼻腔区域表现出降低的冠状腺厚度.
- 胸膜厚度测量似乎与RA患者间歇性肺病的严重程度无关.
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