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Updated: Jun 25, 2025

Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation
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Published on: August 7, 2015

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在MADD中,一个拼接部位变异影响胰腺β细胞和垂体淋巴细胞中的激素表达

Kristiina Pulli1, Jonna Saarimäki-Vire1, Pekka Ahonen1

  • 1Stem Cells and Metabolism Research Program (STEMM), Research Programs Unit, Faculty of Medicine, and.

JCI insight
|May 22, 2024
PubMed
概括

在MAPK激活死亡域 (MADD) 基因中的遗传变异会导致复杂的内分泌疾病. 一个特定的MADD异构体30的缺失会损害胰岛素和黄化激素的产生,影响多个器官系统.

关键词:
贝塔细胞 贝塔细胞 贝塔细胞内分泌学 在内分泌学.遗传性疾病是一种遗传性疾病.神经内分泌调节神经内分泌调节生殖生物学 生殖生物学

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