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在竞争性风险数据中的累积发病率曲线中确定组的一种方法
Marta Sestelo1,2, Luís Meira-Machado3, Nora M Villanueva2
1CITMAga, 15782, Santiago de Compostela, Spain.
Biometrical journal. Biometrische Zeitschrift
|May 22, 2024
概括
本研究引入了一种用于在竞争性风险分析中比较累积发病率函数的新方法. 该程序测试曲线平等,分组不相似的曲线,并确定组组合和数量,在模拟中表现良好.
科学领域:
- 生物统计学 生物统计学
- 生存分析的分析.
- 流行病学 流行病学
背景情况:
- 累积发病率函数 (CIF) 是估计具有竞争风险的事件概率的标准.
- 将CIF进行比较至关重要,但缺乏确定的方法.
- 关于比较竞争风险曲线的现有文献是有限的.
研究的目的:
- 开发一种新的统计程序,用于在竞争性风险下比较累积发病率函数.
- 为了测试CIF的平等性和分组不相似的曲线.
- 自动确定已识别的群体的数量和组成.
主要方法:
- 提出了分析竞争性风险数据的新程序.
- 开发了测试CIF平等和分组曲线的方法.
- 包括对组数及其组成的自动选择.
主要成果:
- 模拟研究表明,对于有限的样本大小,拟议的方法具有良好的数值稳定性.
- 该程序有效地测试了CIF的平等性,并促进了分组.
- 该方法成功地确定了组组合和数量.
结论:
- 开发的程序提供了一个可靠的方法来比较在存在竞争风险的情况下的累积发病率函数.
- 这种方法解决了文献中关于分析和分组竞争性风险数据的重大缺口.
- 该技术通过模拟得到验证,并通过真实世界的数据分析来说明.
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