血清反应因子的过度表达允许呼吸道光滑肌肉的双收缩-增殖表型

Rui Sun1, Xingning Pan1, Erin Ward1

  • 1Meakins-Christie Laboratories, The Research Institute of McGill University Health Centre, Montréal, Québec, Canada.

概括

肌卡丁 (MyoCD) 抑制了气道光滑肌细胞中的Elk-1,但增加的血清反应因子 (SRF) 允许收缩和增殖的表型. 向SRF可以治疗呼吸道疾病.

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