相关实验视频

Updated: Jun 25, 2025

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

面部情绪识别功能和白质微观结构变化在药物原始的,无并发症的自闭症中

Xing Su^1,2, Siuching Kat¹, Hui Wang¹

¹Peking University Sixth HospitaL, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), 51 Huayuan Road, Beijing, 100191, China.

European archives of psychiatry and clinical neuroscience

|May 22, 2024

概括

患有自闭症谱系障碍 (ASD) 的儿童表现出面部情绪识别 (FER) 的受损以及白质微观结构的改变. 这些白质变化可能是ASD观察到的FER缺陷的基础.

科学领域:

神经科学是一个神经科学.
发展心理学发展心理学
生物医学工程生物医学工程

背景情况:

自闭症谱系障碍 (ASD) 与面部情绪识别 (FER) 和白质微观结构变化的缺陷有关.
之前的研究受到了诸如并发症和药物使用等混因素的限制.
在ASD中,FER赤字和白质变化之间的确切关系尚不清楚.

研究的目的:

调查FER能力,白质微观结构,以及它们在未使用药物和无伴随性疾病的ASD个体之间的相互关系.
为了澄清白质变化的作用在FER赤字在这个特定的人群.

主要方法:

包括59名患有自闭症的个体和59名典型发展 (TD) 个体.
使用专用任务评估FER性能 (46个ASD,完成了50个TD).
分析白质微观结构,使用流体空间统计 (TBSS) 和分数异构 (FA) 值.

主要成果:

与TD组相比,ASD组在基本和复杂的FER任务中得分明显较低.
自闭症组在广泛分布的白质道中显示出降低的FA值,包括体,带皮和上纵长.
在TD个体中,复杂的FER表现在几个白质道中与FA负相关;在ASD组中,这种相关性不存在.

结论:

患有自闭症的儿童表现出面部情绪识别的缺陷以及白质微观结构的改变.
白质微结构异常与ASD儿童观察到的面部情感识别缺陷有关.

关键词:

自闭症谱系障碍自闭症谱系障碍面部情绪识别面部情绪识别基于路径的空间统计数据.白物质微观结构白物质微观结构

更多相关视频

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Published on: July 31, 2016

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

相关概念视频

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

Prosopagnosia

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...