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Updated: Jun 25, 2025

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一种新型的同卵性RHOH变异与T细胞功能障碍和反复的机会性感染有关

Jingyu Zhou1, Mengqing Qian1, Ning Jiang1,2,3

  • 1Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Shanghai Medical College, Fudan University, 12 M. Wulumuqi Road, Shanghai, 200040, China.

Journal of clinical immunology
|May 22, 2024
PubMed
概括

一种新的RHOH基因变异通过损害T细胞功能并增加对机会性感染的易感性,导致严重的免疫缺陷. 这一发现突显了RHOH.

关键词:
机会性感染是一种机会性感染.主要免疫缺陷是一个主要的免疫缺陷.在RHOH中,RHOH就是RHOH.一个T细胞细胞.在TCR信号传输中,

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