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Updated: Jun 25, 2025

Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish
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Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish

Published on: April 1, 2021

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低MBOAT7表达,MASH的遗传风险,促进了一种涉及肝细胞TAZ上调的益菌性通路

Mary P Moore1, Xiaobo Wang1, John Paul Kennelly2

  • 1Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.

Hepatology (Baltimore, Md.)
|May 22, 2024
PubMed
概括

在代谢功能障碍相关的脂肪肝炎 (MASH) 中恢复MBOAT7表达减缓了肝纤维化进展. MBOAT7功能的丧失通过通过改变的脂物通过TAZ和印度刺 (IHH) 的上调来加剧MASH纤维化.

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