辩证行为疗法作为治疗成年人抗性抑郁症的干预措施:系统审查和元分析的方案
Larissa Junkes1, Bruno R Gherman1, Jose Carlos Appolinario1
1Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
PloS one
|May 22, 2024
概括
本综述检查了是否将辩证行为疗法添加到抗抑郁药物中,可以改善治疗不良抑郁症的结果. 它提供了关于这种联合方法对成人的有效性和安全性的证据.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 基于证据的医学基于证据的医学.
背景情况:
- 大型抑郁症 (MDD) 是一种普遍的,经常性疾病,严重损害了功能.
- 药物治疗是标准的MDD治疗方法,但30%的人经历了耐治疗抑郁症 (TRD).
- TRD严重影响患者的生活质量,需要新的治疗策略.
研究的目的:
- 进行首次关于这一主题的全面系统审查和元分析.
- 评估结合辩证行为疗法 (DBT) 与抗抑郁药物药物疗法的有效性和安全性,用于TRD的成年人.
- 为了比较这种联合方法与单独的药物治疗.
主要方法:
- 在Cochrane,MEDLINE,Embase,Lilacs,Web of Science和PsycINFO进行系统的文献搜索.
- 包括研究,无论语言或出版日期;手动参考清单选.
- 使用Cochrane偏差风险的质量评估和使用GRADE方法的证据确定性.
主要成果:
- 本部分应在研究完成后填写.
- 分析将综合治疗有效性和安全性结果的数据.
- 统计分析将确定聚合效应的大小和置信区间.
结论:
- 这一系统性审查和元分析将为DBT作为TRD辅助疗法的作用提供关键的见解.
- 研究结果将为管理耐治疗抑郁症的临床实践指南提供信息.
- 这项研究旨在增强患有严重,持久抑郁症状的个体的治疗选择.
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