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Updated: Jun 25, 2025

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通过基于生理学的药理动力学建模来评估通用生物等价性研究中的性别影响 - 德克斯特罗梅索芬修饰释放片的案例研究

Manoj Gundeti1, Aditya Murthy2, Shubham Jamdade1

  • 1Global Clinical Management, IPDO, Dr Reddy's Laboratories Ltd, Hyderabad, India.

Biopharmaceutics & drug disposition
|May 22, 2024
PubMed
概括

通用药物生物等价性 (BE) 研究往往低于女性. 基于生理学上的药理动力学 (PBPK) 建模评估了德克斯特罗梅索芬性能上的性别影响,显示了放弃额外研究和更快地进入市场的潜力.

关键词:
PBPKK PBPK 的意思是什么意思生物等价性 生物等价性德克斯特罗梅多尔 (Dextromethorphan) 是一种可怕的药物.其他气体.性别影响影响性别影响

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