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Updated: Jun 25, 2025

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
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Published on: February 13, 2018

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发现了第一类具有高度选择性的TRPV1抗剂,具有双重止痛和低血糖效应

Chunxia Liu1, Wenxin Wang2, Shiyu Zhao1

  • 1Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, PR China; Henan Key Laboratory of Precision Clinical Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, PR China.

Bioorganic & medicinal chemistry
|May 22, 2024
PubMed
概括

研究人员开发了一种新型TRPV1抗剂CX-3,用于治疗糖尿病神经病变的疼痛和高血糖. 作为安全有效的治疗候选药物,CX-3显示出有前途,而不会导致高温症.

关键词:
止痛药是一种止痛药.敌对者的敌对者血液中的葡萄糖.黄类化合物 黄类化合物在 TRPV1 中.

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