评估喘在神经发育障碍和不良出生结果之间的关系中的作用
Omobola Oluwafemi1, Sneha Manoharan2, Luyu Xie3
1Center for Pediatric Population Health, UTHealth Houston School of Public Health, Dallas, Texas; Department of Epidemiology, Human Genetics and Environmental Sciences, UTHealth Houston School of Public Health, Dallas, Texas; Department of Epidemiology, Human Genetics and Environmental Sciences, Southwest Center for Occupational and Environmental Health, UTHealth Houston School of Public Health, Houston, Texas.
喘不会改变出生不良结果和神经发育障碍 (NDD) 之间的联系. 然而,NDD在美国儿童中更常见,特别是在黑人儿童中.
科学领域:
- 儿科健康 儿科健康
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 了解神经发育障碍 (NDD) 的差异对于有针对性的干预至关重要.
- 调查喘作为不良出生结果和跨种族群体NDD的效果修饰者的作用对于解决可变易感性至关重要.
研究的目的:
- 检查喘是否改变了不良分娩结果 (早产,低出生体重) 和NDD之间的关联.
- 分析具有不良出生结果的儿童中NDD患病率的种族差异.
主要方法:
- 利用了来自国家儿童健康调查的数据 (131,774名0-17岁的儿童).
- 基于出生结果计算的NDD的患病率和概率比率,按喘状况分层.
- 在不同种族群体中评估了喘,出生结果和NDD之间的相互作用.
主要成果:
- 喘并没有显著改变不良分娩结果和NDD之间的关系.
- 有不良出生结果的儿童表现出更高的NDD患病率.
- 与非西班牙裔白人儿童相比,具有不良出生结果的非西班牙裔黑人儿童的NDD患病率较高.
结论:
- 喘不是不利的出生结果和NDD的效果修饰剂.
- 不利的出生结果与增加的NDD患病率有关,特别是在黑人儿童中.
- 建议对具有不良出生结果的儿童进行NDD查,特别是少数民族.
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