相关实验视频
Updated: Jun 25, 2025

09:36
Measurement of Spatial Stability in Precision Grip
Published on: June 4, 2020
3.2K
确定与触发指相关的非遗传因素
Leon Guggenheim1, Youngjoo Kang1, Dominic Furniss2
1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7LD, UK.
概括
触发指 (TF) 与糖尿病,手腕道综合征和杜普伊特伦病密切相关. 这项大型研究证实了已知的风险因素,并揭示了新的联系,有助于理解TF的病理生理学.
科学领域:
- 医学研究 医学研究
- 流行病学 流行病学
- 整形外科 整形外科 整形外科
背景情况:
- 触发指 (TF) 的非遗传因素已经在小队伍中进行了研究.
- 本研究提供了使用大量基于人口的数据集对TF协会的全面分析.
研究的目的:
- 识别和量化表型变量和触发指 (TF) 之间的关联的强度.
- 为了提供一个更完整的图片的TF风险因素及其相互关系.
主要方法:
- 病例控制研究使用来自英国生物库的横截面数据.
- 采用多变量逻辑回归来分析许多表型因素与TF之间的关联.
主要成果:
- TF与年龄,女性性别,体重指数,手管综合征,杜普伊特伦病,糖尿病,HbA1c水平,甲状腺功能低下症和类风湿性关节炎有显著的关联.
- 与手腕道综合征 (OR 9.59) 和杜普伊特伦病 (OR 4.89) 观察到强烈的关联.
结论:
- 这项研究证实了TF的已知风险因素,包括糖尿病,手腕道综合征,年龄和女性性别.
- 确定了与杜普伊特伦病的新兴关联,这表明与TF有着共同的病理生理学,独立于手腕道综合征.
更多相关视频
相关概念视频
Autoimmune Disorders
417
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
417
Polygenic Traits
65.7K
When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
65.7K
Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
Gene-Environment Interactions
293
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
293

