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Updated: Jun 25, 2025

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维尼托克拉克斯作为免疫代谢调节剂,增强了针对白血病的采用NK细胞免疫疗法

Yan Wang1, Beibei Huang2, Tingting Liang1

  • 1Department of Hematology, The First Affiliated Hospital of USTC, Key Laboratory of Immune Response and Immunotherapy, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China; Institute of Immunology, The CAS Key Laboratory of Innate Immunity and Chronic Disease, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Cell reports. Medicine
|May 22, 2024
PubMed
概括

作为BCL-2抑制剂的Venetoclax直接激活自然杀手 (NK) 细胞,增强它们对急性髓性白血病 (AML) 的杀癌能力. 这种药物增强NK细胞功能,并显示出改善免疫疗法策略的前景.

关键词:
这就是NF-κBB.有关RNA测序的RNA测序急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.这就是贪,贪.细胞毒性 细胞毒性免疫学的突触.免疫疗法 免疫疗法线粒体呼吸系统的呼吸过程自然杀手细胞是自然杀手细胞.维尼托克莱克斯 (Venetoclax) 是一个

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