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Updated: Jun 25, 2025

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化脱酶2缺乏会通过线粒体功能障碍和纤维细胞衰老加剧肺纤维化

Yanqiu Wei1, Shuwei Gao2, Chen Li2

  • 1Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China; National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.

The American journal of pathology
|May 22, 2024
PubMed
概括

脱酶2 (ALDH2) 缺乏通过增强纤维细胞激活促进肺纤维化. 激活ALDH2可能为这种致命的肺病提供了一个新的治疗策略.

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