怀孕13周之前的药物治疗和手术性流产以及精神疾病的风险
Julia R Steinberg1, Thomas M Laursen2, Øjvind Lidegaard3
1Department of Family Science, University of Maryland, College Park, MD.
American journal of obstetrics and gynecology
|May 22, 2024
概括
药物治疗和手术性堕胎不会在短期或长期增加心理健康障碍的风险. 这项以人口为基础的研究发现,与前一年相比,在任何一种堕胎方法后,精神病诊断的风险都没有增加.
科学领域:
- 生殖健康 生殖健康
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 自2000年米费普里斯顿的FDA批准以来,药物流产在全球变得越来越普遍.
- 现有的研究表明,堕胎不会增加心理健康风险.
- 没有以人口为基础的研究专门比较了药物治疗和手术性堕胎的心理健康障碍风险.
研究的目的:
- 调查药物治疗或手术性堕胎是否与精神健康障碍的增加有关.
- 检查这些堕胎方法的短期和长期风险.
主要方法:
- 一项前性队列研究使用了丹麦人口登记册.
- 包括72,424名女性 (年龄在12-38岁) 在2000-2018年期间进行了第一季度堕胎.
- 在堕胎后的5年内,对精神病诊断的参与者进行了跟踪,并对许多共同变量进行了调整.
主要成果:
- 与前一年相比,在药物治疗或手术性堕胎后的一年内首次精神病诊断的风险没有差异.
- 药物治疗和手术性堕胎后,随着时间的推移 (1-5+年) 精神病诊断的风险下降.
- 药物流产的调整发生率比率 (aIRR) 为1.02 (1年) 和0.58 (5年+).
- 程序性堕胎的调整后发生率比率 (aIRR) 为0.94 (1年) 和0.54 (5年+).
结论:
- 无论是药物治疗还是手术性堕胎都不会增加精神健康障碍的风险.
- 在任何一种堕胎方法后,精神病诊断的风险在短期或长期内都不会增加.
- 研究结果支持堕胎程序不会对长期心理健康产生负面影响.
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