一种基于遗传算法的方法,用于预测涉及CYP2C8或CYP2B6的代谢药物相互作用

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Updated: Jun 25, 2025

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
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High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method

Published on: May 21, 2018

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Veronica Di Paolo1, Francesco Maria Ferrari2, Davide Veronese1

  • 1Laboratory of Drug Metabolism, Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.

Journal of pharmacological and toxicological methods
|May 22, 2024
PubMed
概括

一个新的遗传算法可以从CYP2B6和CYP2C8酶活性预测药物相互作用 (DDI). 这种工具有助于确定使用CYP2B6或CYP2C8基质与相互作用药物的安全药物剂量.

关键词:
临床药理动力学 临床药理动力学细胞染色体P450的使用.药物相互作用 药物相互作用遗传算法 遗传算法 遗传算法

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