从童年开始的动脉样硬化:具体特征
Anastasia V Poznyak1, Alexey A Yakovlev2, Mikhail А Popov3
1Institute for Atherosclerosis Research, Moscow 121609, Russia.
Journal of biomedical research
|May 22, 2024
概括
儿童动脉样硬化,经常被忽视,可以在胎儿发育和婴儿期开始. 关键的因素包括营养,感染和母亲/婴儿体重过重,突出了早期生命风险.
科学领域:
- 心血管医学 心血管医学
- 儿科健康 儿科健康
- 发展生物学 发展生物学
背景情况:
- 动脉样硬化是一种普遍的心血管疾病,通常与衰老有关.
- 新出现的证据表明动脉样硬化可以在生命早期发展,包括子宫内和儿童阶段.
- 传统的研究一直专注于与年龄相关的动脉样硬化,忽视了早期发病的疾病.
研究的目的:
- 审查儿童时期动脉样硬化的发育过程.
- 识别和检查早期动脉样硬化的先决条件.
- 综合有关非成人动脉样硬化的当前知识.
主要方法:
- 关于动脉样硬化现有研究的文献综述.
- 分析导致儿童动脉样硬化的因素.
- 检查从胎儿生命到儿童时期的发育途径.
主要成果:
- 动脉样硬化发展可以在胎儿发育期间开始,并持续到童年.
- 儿童动脉样硬化受营养状况,先前的传染病和母亲/婴儿体重的影响.
- 早期生活因素对动脉样硬化发展轨迹产生重大影响.
结论:
- 动脉样硬化不仅仅是老年人的疾病;它起源于儿科.
- 了解儿童动脉样硬化的先决条件对于早期干预和预防策略至关重要.
- 对早期生命因素的进一步研究是有必要的,以对抗动脉样硬化的全球负担.
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