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Updated: Jun 25, 2025

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis
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Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis

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使用短读和长读测序来对白血病细胞系REH进行多组性表征

Mariya Lysenkova Wiklander1,2, Gustav Arvidsson1,2, Ignas Bunikis2,3,4

  • 1Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Life science alliance
|May 22, 2024
PubMed
概括

这项研究提供了对REH细胞系的全面基因组和转录组分析,这是一种儿科B细胞急性淋巴细胞白血病 (ALL) 的模型. 综合测序方法揭示了关键的遗传改变和融合基因,为白血病研究提供了有价值的数据.

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A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations09:34

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

Published on: October 25, 2018

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Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients13:21

Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia Patients

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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