对精神病心理干预试验中的物质使用:样本纳入,次要措施和干预有效性
Lauren Halsall1, Anastasia Ushakova2, Steven Jones1
1Division of Health Research, Spectrum Centre for Mental Health Research, Lancaster University, Lancaster, England.
Schizophrenia bulletin
|May 22, 2024
概括
对于精神病的心理干预很少包括或测量酒精和物质使用障碍 (A/SUD). 需要进行更多的研究,以确定与精神病和A / SUD同时发生的个体的有效治疗方法.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 成 药物 药物 药物 药物
背景情况:
- 临床指南建议综合治疗同时发生的精神病和酒精或物质使用障碍 (A/SUD).
- 对A/SUD患者精神病的心理干预措施的有效性尚不清楚.
- 目前的证据基础对这种共同疾病患者群体的治疗决策提出了挑战.
研究的目的:
- 系统地审查精神病心理干预的随机对照试验 (RCT).
- 调查在这些RCT中A/SUD的纳入和测量.
- 总结心理干预对患有同时出现A/SUD的个体精神病的疗效.
主要方法:
- 对用于精神病的心理干预的RCT进行系统审查.
- 对样本纳入标准和与A/SUD相关的二次结果措施的分析.
- 来自包括A/SUD个体在内的试验发现的叙述综合.
主要成果:
- 大多数 (60.3%) 的确定的试验都排除了患有A/SUD的个体.
- 在基线 (6.1%) 或作为次要结局 (2.3%) 时,A/SUD很少被测量.
- 目前还没有足够的证据来证实任何特定的心理干预对伴随性A/SUD精神病的疗效,尽管精神教育和元认知疗法需要进一步研究.
结论:
- 同时发生的A / SUD在精神病心理干预的RCT中基本上被忽视.
- 目前的证据基础不足以指导患有精神病和A / SUD同时出现的人的治疗选择.
- 进一步的研究对于开发和验证有效的心理干预对这一群体至关重要.
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