LLL 44-4:急性疾病和危急疾病中的微量营养素
Angélique M E de Man1, Karin Amrein2, Michael P Casaer3
1Amsterdam UMC, Location Vrije Universiteit, Department of Intensive Care, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands.
Clinical nutrition ESPEN
|May 22, 2024
概括
微量营养素 (MN),对于重症监护至关重要,对抗炎症和氧化应激. 满足增加的MN需求对于重症患者的免疫防御和组织修复至关重要.
科学领域:
- 临床营养学 临床营养学
- 关键护理医学 关键护理医学
- 生物化学 生物化学
背景情况:
- 微量营养素 (MN),包括微量元素和维生素,是必不可少的饮食成分.
- 危急疾病涉及炎症和氧化应激,增加MN需求.
- 诸如急性损伤,肠道衰竭,烧伤和创伤等疾病会导致显著的MN损失.
研究的目的:
- 突出微量营养素在重症患者中的关键作用.
- 为了强调严重疾病中缺乏的需求和风险的增加.
- 为维持适当的微量营养素状态提出战略.
主要方法:
- 审查微量营养素在抗氧化剂和免疫防御中的作用.
- 分析导致微量营养素耗尽的因素在危急疾病.
- 讨论在炎症期间解释微量营养素血液水平的挑战.
主要成果:
- 微量营养素是内源性抗氧化剂和免疫功能的组成部分.
- 重症患者面临急性微量营养素耗尽和缺乏的高风险.
- 炎症使微量营养素状态生物标志物的解释变得复杂.
结论:
- 确保足够的微量营养素摄入对于支持严重疾病中的防御和组织修复至关重要.
- 需要实用策略来应对提高的微量营养素需求.
- 积极管理微量营养素状况对于患者的治疗结果至关重要.
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