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Updated: Jun 25, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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TIMP-1是髓状树突细胞中MHC-I表达的激活剂,对瘤免疫性有影响

Miriam Langguth1, Eleftheria Maranou1, Saara A Koskela1

  • 1Medical Immune Oncology Research Group (MIORG), Institute of Biomedicine, Faculty of Medicine, University of Turku, Turku, Finland.

Genes and immunity
|May 22, 2024
PubMed
概括

组织抑制金属蛋白酶-1 (TIMP-1) 增强了黑色素瘤中的树突细胞 (DC) 功能,促进了CD8+ T细胞的反应. 这一发现为改善癌症免疫治疗疗效提供了一个新的目标.

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