儿童和青少年精神病学中的休息状态功能性大脑连接:我们现在在哪里?
Lucina Q Uddin1,2, F Xavier Castellanos3,4, Vinod Menon5,6,7
1Department of Psychiatry and Biobehavioral Science, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA, USA. lucina@ucla.edu.
概括
休息状态功能性MRI揭示了神经发育条件中的广泛的大脑网络变化. 需要进一步的研究,以了解发育变化和个性化儿童精神病治疗.
科学领域:
- 神经科学是一个神经科学.
- 儿童和青少年精神病学
- 神经成像是一种神经成像.
背景情况:
- 休息状态功能磁共振成像 (rsfMRI) 显著提高了我们对大脑功能的理解.
- 在rsfMRI的30周年纪念活动中,强调了它对研究内在功能性大脑架构的影响.
- rsfMRI揭示了神经发育条件中的广泛的电路改变.
研究的目的:
- 审查rsfMRI对儿童和青少年精神病学的影响.
- 讨论从研究内在功能性大脑架构中获得的见解.
- 确定个性化儿童精神病学的挑战和未来方向.
主要方法:
- 对儿童和青少年精神病学中rsfMRI现有文献的综述.
- 分析来自大型rsfMRI数据集的见解.
- 讨论方法和理论方面的挑战.
主要成果:
- 神经发育条件与大规模大脑网络的更广泛变化有关,而不是以前认为的.
- 人口神经科学和数据共享使得基于大脑的亚型的识别成为可能.
- 在理解功能连接的发展变化方面仍然存在重大挑战.
结论:
- rsfMRI在理解神经发育状况方面取得了突破.
- 需要进一步的研究来应对方法和理论方面的挑战.
- 未来的方向包括跨物种,多模式神经成像,数据协调和自然主义fMRI范式.
更多相关视频
08:23A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
11.2K
07:13Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
Published on: May 27, 2020
6.6K
相关概念视频
01:14Brain Imaging
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
01:18Cognitive Development During Adolescence
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the recognition that people have...
01:24Revisionist Views of Adolescent and Adult Cognition
A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are themselves.