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从CAD/CAM splint材料中释放的双甲.

Tristan Hampe1, Julia Liersch1, Bernhard Wiechens1,2

  • 1Department of Prosthodontics, University Medical Center Göttingen, Göttingen, Germany.

European journal of oral sciences
|May 23, 2024
PubMed
概括

研究了从CAD/CAM具材料中释放的双甲 (BPA) 的情况. 所有测试材料都释放出大量的BPA,其度超过欧盟标准.

关键词:
牙科材料 牙科材料内分泌干扰者是什么?内分泌干扰者聚碳酸聚碳酸的使用情况聚甲基甲基酸聚甲基甲基酸

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科学领域:

  • 材料科学 材料科学 材料科学
  • 分析化学 分析化学
  • 牙科材料 牙科材料

背景情况:

  • 双A (BPA) 是一种化学化合物,用于各种塑料和树脂材料.
  • 人们对BPA从牙科材料出口腔环境存在担忧.
  • 计算机辅助设计/计算机辅助制造 (CAD/CAM) 越来越多地用于制造牙.

研究的目的:

  • 量化和比较四种不同的CAD/CAM splint材料中的双甲 (BPA) 释放.
  • 评估这些材料中的 BPA 化是否超过已确定的安全值.

主要方法:

  • 测试了四种CAD/CAM线材料 (3种基于聚碳酸盐,1种基于聚甲基甲酸盐).
  • 圆柱形样本被浸入HPLC级水中,并在37°C进行24小时的化.
  • 使用高性能液体染色学-并联质谱法 (HPLC-MS/MS) 分析了BPA度.

主要成果:

  • 所有经过测试的CAD/CAM片材料都释放出大量的BPA.
  • BPA化因材料而异,聚碳酸基材料的释放率高于聚甲基甲酸基材料的释放率.
  • 计算出的每支 splint 体积的 BPA 度超过了欧盟可容忍每日摄入量 (TDI) 的 1.32 到 6.16 倍.

结论:

  • 在牙科实践中,CAD/CAM线材料可能是BPA暴露的重要来源.
  • 高水平的BPA化要求对材料安全性和潜在的健康影响进行进一步调查.
  • 材料选择和临床处理可能会影响CAD/CAM片中的BPA释放.