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Updated: Jun 25, 2025

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
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人类胰岛素作为1型糖尿病的抗原和保护剂

Nitin P Amdare1, Leonard D Shultz2, Dale L Greiner3

  • 1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.

European journal of immunology
|May 23, 2024
PubMed
概括

研究人员开发了一种新的小鼠模型来研究1型糖尿病 (T1D). 这个模型有助于识别人体胰岛素 (hIns) T 细胞表位,这对于理解T1D自身免疫反应至关重要.

关键词:
动物模型动物模型这是一种自身免疫力.CD8 T 细胞 CD8 T 细胞在MHC中,MHC是最重要的.转基因模型的转基因模型

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