在非洲裔人口中,子宫内膜癌的生存率
Heidy N Medina1,2, Frank J Penedo2,3, Jacqueline Deloumeaux4
1Department of Public Health Sciences, University of Miami School of Medicine, Miami, FL 33136, United States.
American journal of epidemiology
|May 23, 2024
概括
美国和加勒比地区的黑人妇女面临更糟糕的子宫内膜癌 (EC) 生存率. 这种生存劣势不是美国特有的,加勒比黑人女性对侵略性的EC类型的结果较差.
科学领域:
- 妇科瘤学 妇科瘤学
- 流行病学 流行病学
- 癌症的差异 在癌症的差异
背景情况:
- 在美国,黑人人口的子宫内膜癌 (EC) 存活率较低.
- 目前尚不清楚这种生存劣势是否仅限于美国.
研究的目的:
- 为了调查黑人女性患子宫内膜癌的较差生存结果是否是美国特有的.
- 为了比较美国的黑人妇女和法国加勒比地区的非洲裔黑人妇女之间的EC生存率.
主要方法:
- 分析了来自佛罗里达州,马丁尼克和瓜德罗普的28,213例子宫内膜癌病例.
- 卡普兰-梅尔和考克斯的比例危险模型被用来比较生存率.
- 模型按EC组织学和种族/种族分层 (美国非西班牙裔白人,美国非西班牙裔黑人,加勒比黑人).
主要成果:
- 美国非西班牙裔黑人 (NHB) 妇女和加勒比黑人妇女的死亡风险高于美国非西班牙裔白人 (NHW) 妇女的所有EC类型.
- 在美国NHB妇女和加勒比黑人妇女之间没有观察到 Endometrioid EC 的显著生存差异.
- 与美国NHB女性相比,非子宫内膜异位症的加勒比黑人妇女的死亡风险比美国NHB妇女高40%.
结论:
- 患有子宫内膜癌的黑人妇女的生存率较低并不仅限于美国.
- 与美国相比,加勒比地区的黑人妇女的侵略性非子宫内膜组织的生存率要比加勒比地区的黑人妇女要糟糕得多.
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