检查在息治疗中的老年人中潜在不适当的药物使用:一项全面的研究
Ozlem Kirci1, Mahcube Cubukcu2, Remzi Bahsi3
1Samsun Training and Research Hospital, Clinic of Family Medicine, Samsun, Turkey.
Heliyon
|May 23, 2024
概括
在接受息治疗的老年人中,多药和潜在不合适的药物 (PIM) 是常见的. 解决多药学问题可能有助于减少PIM并改善患者的治疗结果.
科学领域:
- 老年病的医生 老年病的医生
- 抚慰性护理是一种缓解性护理.
- 临床药房 临床药房
背景情况:
- 多药和潜在不合适的药物 (PIMs) 是老年患者,特别是那些接受息治疗的患者的重大担忧.
- 优化药物治疗方案对于改善生活质量和减少这种脆弱人群的不良事件至关重要.
研究的目的:
- 确定在接受息治疗的老年人中多药和PIM的流行率.
- 为了确定与多药学相关的因素.
- 评估TIME标准在评估药物适当性的有用性.
主要方法:
- 一项涉及213名息治疗患者的横截面描述性研究.
- 数据收集包括迷你营养评估简单表格,卡茨日常生活活动量表和查尔森并发症指数.
- 多种药物定义为≥5种药物;PIMs使用 TIME-to-START和 TIME-to-STOP标准进行评估.
主要成果:
- 多药性在59.2%的患者中流行,高多药性 (≥10种药物) 在10.8%的患者中流行.
- 在多药和婚姻状况,摔倒史和人类测量测量之间发现了显著的相关性.
- 潜在不适当的药物使用率很高 (56.3%),在18.3% (TIME-to-START) 和48.4% (TIME-to-STOP) 中发现了PIM.
- 在使用多种药物的患者中观察到较高的PIM率 (p < 0.001).
结论:
- 在接受息治疗的老年人中,多药和PIM非常普遍.
- 多药与PIMs的风险增加有关.
- 使用TIME标准可以帮助减少在息护理环境中不适当的药物使用.
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