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在葡萄牙COVID-19之前的呼吸道病毒感染:一个单一中心研究研究
Vera Durão1,2, Vera Clérigo2, Paulo Durão3,4
1Hospital de Vila Franca de Xira, Lisboa, Portugal.
Heliyon
|May 23, 2024
概括
在葡萄牙的住院患者中,呼吸道病毒如鼻病毒,流感和RSV是常见的. 老年人和婴儿面临更高的风险,老年和男性性别增加死亡风险.
科学领域:
- 医学微生物学 医学微生物学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 呼吸系统病毒 (RV) 对健康构成重大负担,特别是在脆弱人群中.
- 了解VR的患病率和临床影响对于公共卫生战略至关重要.
研究的目的:
- 在葡萄牙塞图巴尔 (Setúbal) 的住院患者中识别呼吸道病毒.
- 为了将病毒发现与临床特征和结果相关联.
- 为在SARS-CoV-2大流行之前提供VR流行病学的见解.
主要方法:
- 追溯分析了948个鼻腔/耳鼻口抽样.
- 使用逆转录-聚合酶链反应 (RT-PCR) 进行的测试.
- 病毒检测与患者人口统计和临床数据的相关性.
主要成果:
- 鼻膜病毒/肠膜病毒,流感和人类呼吸道同胞病毒 (hRSV) 是最常见的.
- 一半的患者符合急性呼吸道感染 (ARI) 或类似流感的疾病 (ILI) 的标准.
- 年龄较大与较低的ARI/ILI风险相关,但死亡率较高;hRSV增加了住院治疗风险.
结论:
- 呼吸道病毒感染显著影响住院患者,特别是患有支气管炎的婴儿和患有肺炎的老年人.
- 这项研究提供了在COVID-19大流行之前葡萄牙RV流行病学的关键基线.
- 临床见解强调了针对高风险群体进行有针对性的干预的必要性.
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