慢性血液透析患者血清维生素B12缺乏症
Mehdi Mushtaq1,2, Muhammad Rehan Usmani3, Najia Hameed1
1Nephrology, Patel Hospital, Karachi, PAK.
Cureus
|May 23, 2024
概括
在血液透析患者中,维生素B12缺乏是常见的,影响22.2%. 更长的血液透析持续时间与这种缺陷有显著的相关性,强调需要定期监测.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床营养学 临床营养学
- 生物化学 生物化学
背景情况:
- 维生素B12对于生理功能至关重要.
- 接受血液透析的患者有维生素B12缺乏的风险.
- 缺乏可以导致不良健康影响.
研究的目的:
- 为了确定血液透析患者维生素B12缺乏的频率.
- 调查维生素B12缺乏与临床参数之间的关联.
- 评估血液透析持续时间对维生素B12水平的影响.
主要方法:
- 在卡拉奇的两家医院进行了横截面研究.
- 包括135名接受维持血液透析的成年功能衰竭患者.
- 使用千平方测试来确定关联的统计分析.
主要成果:
- 在135名患者中,30名 (22.2%) 患有维生素B12缺乏症.
- 血清维生素B12水平的平均值为411.61±224.95ppg/ml.
- 在维生素B12缺乏和血液透析持续时间之间发现了显著的关联 (p=0.013).
结论:
- 慢性血液透析患者中很大一部分患有维生素B12缺乏症.
- 维生素B12缺乏与血液透析的持续时间有显著联系.
- 定期的维生素B12检测建议用于血液透析患者,以防止并发症.
相关概念视频
01:27Dialysis
294
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
294
01:25Role of Vitamins in Maintaining Bone Health
3.3K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.3K