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PRECISE-DYAD协议:连接撒哈拉以南非洲的母亲和婴儿健康轨迹

Rachel Craik^1,2, Marie-Laure Volvert¹, Angela Koech³

¹Department of Women and Children's Health, School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

Wellcome open research

|May 23, 2024

概括

在肯尼亚和冈比亚,PRECISE-DYAD研究跟踪了两年的母亲和孩子,检查了正常和复杂怀孕后的健康结果. 这项研究旨在提高对长期母亲和儿童健康轨迹的理解.

科学领域:

孕产妇和儿童健康研究
撒哈拉以南非洲的流行病学
纵向队列研究是指纵向队列研究.

背景情况:

PRECISE-DYAD研究是一组观察性队列,在冈比亚和肯尼亚跟踪母婴对.
队列包括没有并发症的怀孕和那些怀孕高血压,胎儿生长限制,早产和/或死产.

研究的目的:

加强对撒哈拉以南非洲的健康和疾病途径的流行病学和机制学理解.
为了研究母亲和儿童的长期健康轨迹,在各种妊娠结果之后.
确保为队列维护和持续研究提供进一步的资金.

主要方法:

从最初的PRECISE研究中对大约4200个母婴二进行了为期两年的随访.
收集额外的生物样本和关于母亲和儿童健康的临床数据,包括饮食和心脏病评估.
包括心理健康,出生经验,财务支出,儿童发育 (神经发育,环境,生活质量),视力和自闭症谱系障碍风险评估的病例控制要素.
使用空气/水质,地理,人口和行为数据开发个人环境暴露模型.

主要成果:

数据收集正在进行中,重点是详细的母婴健康信息.
分析将提供关于怀孕结果对长期健康的影响的见解.
这项研究旨在确定环境暴露与健康结果之间的联系.

结论:

在撒哈拉以南非洲地区,精确度-DYAD研究对了解母亲和儿童健康至关重要.
调查结果将为公共卫生战略和干预提供信息.
需要继续进行研究,以充分阐明长期健康影响.

关键词:

孕产妇健康孕产妇健康空气质量空气质量空气质量生物存储库生物存储库儿童健康儿童健康全球卫生健康全球卫生健康神经发育的神经发育怀孕并发症怀孕并发症

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