治疗治疗后肝细胞癌的辅助疗法:几个未回答的问题
Le Li1,2, Zhen-Zhen Li3, Li-Xin Pan1
1Hepatobiliary Surgery Department, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China.
Journal of clinical and translational hepatology
|May 23, 2024
概括
肝癌手术后的辅助疗法可以减少复发,但全球范围内的指导方针有所不同. 本综述探讨了肝细胞癌 (HCC) 治疗当前的选择和挑战.
科学领域:
- 肝胆瘤学 肝胆瘤学
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 肝细胞癌 (HCC) 经常在治疗后复发,导致预后不佳.
- 肝切除术和切除术是主要的治疗选择,但复发率达到70%.
研究的目的:
- 审查当前的辅助疗法选择,以治疗肝切除术或切除HCC.
- 讨论国际指南中辅助治疗建议中的差异和困境.
主要方法:
- 对肝细胞癌的现有辅助疗法的文献综述.
- 东方 (中国) 和西方 (AASLD) 辅助治疗指南的比较分析.
主要成果:
- 辅助疗法,如抗病毒疗法,TACE,TCM和免疫检查点抑制剂,显示出减少复发和改善生存的潜力.
- 在中国和西方的指导方针之间存在很大的差异,这些指导方针涉及HCC推的辅助治疗.
结论:
- 对HCC的标准辅助疗法缺乏全球共识,需要进一步的研究和指导方针协调.
- 了解辅助治疗建议的区域差异对于优化手术后HCC管理至关重要.
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