基因组选择对养猪目标的预测好处
Md Sharif-Islam1, Julius H J van der Werf2, Benjamin J Wood3
1AGBU, a Joint Venture of NSW Department of Primary Industries, University of New England, Armidale, New South Wales, Australia.
概括
在养猪中,基因组选择 (GS) 与传统方法相比,显著提高了整体遗传收益. 有有限数据或遗传能力低的特征,如母猪的寿命长度,显示GS带来了最大的改善.
科学领域:
- 动物育种与遗传学
- 量化遗传学 量化遗传学
- 基因组选择 基因组选择
背景情况:
- 传统的育种计划在实现最佳遗传收益方面存在局限性.
- 基因组选择 (GS) 通过将基因组信息纳入育种决策,提供了潜在的进步.
研究的目的:
- 与传统方法相比,在养猪计划中通过基因组选择 (GS) 实现的额外遗传收益的评估.
- 评估基准种群大小对GS有效性的影响.
主要方法:
- 一个确定性模拟模型被用来预测遗传收益.
- 用基因组信息和没有基因组信息的场景进行了比较.
- 选择精度和每轮选择预测的遗传收益被评估为 sire 和母线.
主要成果:
- 在GS情景下,总体繁殖目标响应在母线中增加了9-56%,在父线中增加了3.5-27%.
- 具有有限的表型数据或低遗传性的特征 (例如,母猪寿命, litter 尺寸,生存率,肉质) 显示出最大的额外收益.
- 易于测量的特征 (例如,背部脂肪,平均每日增益) 与传统育种相比,GS的增益较小.
结论:
- 基因组选择提高了养猪目标的整体遗传收益.
- GS的有效性受参考群体的大小的影响.
- 对于难以测量或遗传性较低的特征,GS提供了实质性的好处,尽管在容易测量的特征上有权衡.
相关概念视频
Plant Breeding and Biotechnology
18.9K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
18.9K
Genetic Screens
4.9K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
4.9K


